Square-Immune™ Subscription - 1x every 3 Months

SADBE™ (Squaric Acid Dibutyl Ester), the active ingredient of Square-Immune, is a topical immunosensitizer, like poison ivy, and has been used medically for 40 years in various immune conditions. Square-Immune was in placebo-controlled clinical trials at Harvard and Stanford and other sites in 140 patients, and it cut cold sore outbreaks by 60%.

In clinical trials conducted by Square-Immune™, SADBE™ was shown to: 

• Triple the time to the next cold sore outbreak compared to placebo.
• Reduce the number of outbreaks by 2.6 times compared to placebo.
• Shift the immune response from an antibody-based reaction to a stronger, T-cell-driven response.
• Increase production of anti-viral protein Interferon-Gamma (produced by T cells) by 1,100%, indicating strong immune response.

Square-Immune™ is a topical solution you apply using the included cotton swab. Simply dab a penny-sized amount (about 2 cm) onto clean, dry skin on the inner side of your upper arm. Apply only to that spot. Let it absorb, then leave it on for at least three hours before washing off. You can cover it with a Band-Aid if preferred, and we recommend washing the area before bed to prevent transfer.

One dose of Square-Immune™ is designed to boost your immune response for up to three months, so we recommend applying it once every three months. That said, some customers find that additional doses between scheduled applications work better for them. If you’d like the flexibility to apply more frequently, we recommend choosing the 1-year supply, which includes enough solution for multiple doses throughout the year.

Square-Immune™ begins to create changes in your immune system within two weeks. In regards to cold sores (oral herpes), in clinical trials, most people saw a reduction in cold sore outbreaks within three to six weeks of their first dose. Expect a similar time frame for results for other immune conditions like fibromyalgia and allergies. That said, every immune system is different. Some users report feeling a difference—like fewer or milder symptoms—within just a few days of applying their first dose.

The evidence for Square-Immune for immune conditions:
Warts. Warts of all sorts—common warts, plantar warts, and genital warts—are caused by human papilloma virus (HPV). SADBE, the active ingredient of Square-Immune, and other topical immunosensitizers, have been used by dermatologists for 40 years to treat warts.
Cold sores and herpes. Cold sores (aka oral herpes) and genital herpes are caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2). The Square-Immune formulation has been tested in placebo- controlled clinical trials at Harvard and Stanford Universities and three other clinical sites, in persons with 4 or more cold sore outbreaks per year and it reduced cold sore outbreaks by 60% compared to placebo.
HIV and AIDS. In several case study reports, SADBE and other topical immunosensitizers were shown to increase immune function and T-cell counts in persons with AIDS or HIV infection.
Fibromyalgia, Long-COVID, and Chronic Fatigue Syndrome (CFS). These are all characterized by symptoms of fatigue, brain fog, and general pain. For many years doctors were not sure what caused fibromyalgia and many thought it was psychosomatic. It is now clear that many cases are caused by viral infections, particularly Epstein-Barr virus (EBV) infection. Epstein-Barr virus causes mononucleosis and almost everyone is infected with it at some point. EBV infection is permanent. The virus infects B cells and lives in those cells your whole life. Ordinarily your immune system controls it and keeps it dormant. This is exactly like Herpes Simplex Virus (HSV) that causes cold sores and genital herpes. HSV is also a life-long infection that is never cleared. And EBV and HSV are both types of herpesvirus. Some cases of fibromyalgia and CFS are caused by EBV infection. Others are undoubtedly caused by HSV infection. Long-COVID has essentially the same symptoms and is caused by COVID infection (or I suspect sometimes caused by the COVID vaccines).
At least some and possibly most cases of fibromyalgia and CFS are caused by viral infections that continue to activate or otherwise mess up and confuse your immune system. Since Square-Immune
works to improve immune control of herpes virus infections, it stands to reason it will do the same for EBV and COVID infections and other viral infections. Thus, it should help with fibromyalgia, long-COVID, and CFS. Some customers have reported that it has helped with their long-COVID and fibromyalgia.
Autoimmune diseases. SADBE and other topical immunosensitizers have been used successfully to treat alopecia areata, an autoimmune form of hair loss where the immune system attacks hair follicle roots, causing the hair to fall out. However, it needed to be applied to the entire effected area of the scalp.
From that, we believe that Square-Immune is likely to be helpful with any autoimmune disease, such as rheumatoid arthritis, psoriasis, and lupus erythematosus.
Allergies. Allergies are similar to autoimmune diseases in that they involve an inappropriate immune
response. In autoimmune disease, your immune system attacks certain tissues in your own body. In allergies, the immune system reacts to pollen or certain foods or other substances that are not actually harmful, and that reaction harms your body.
One Square-Immune customer who had such severe hay fever allergies that she was hospitalized for it reported that after her first dose of Square-Immune she had her best allergy season in years.
Colds and Flu. Unlike herpes simplex and Epstein-Barr virus infections, which are permanent, cold and flu virus infections are temporary and are cleared from your body. My own experience is that, while I still get colds sometimes, they are milder and less frequent than before I started using Square-Immune.