How It Works
The key ingredient of Square-Immuneâ„¢ is SADBE (Squaric Acid Dibutyl Ester), a compound that helps train your immune system to fight outbreaks before they even start.Â
Apply Square-Immuneâ„¢ topically to the underside of your upper arm once. This creates an immune response in your skin that resets and improves your immune response to the herpes simplex virus that causes cold sores. We recommend reapplying once every 3 months.
Square-Immune™ is not a drug, it’s a topical immune booster that stimulates a natural immune response by activating your T cells. It never enters your body but rather reacts with proteins in your skin to cause an immune response.
Which Size Should You Order?



Genital Herpes | Cold Sores | Doses | Price | |
---|---|---|---|---|
A Single Dose of Square-Immune™ - OR Save 29% with a subscription or 57% with a year-supply! | ✅ | ✅ | 1 Dose | $59.99 |
1-Year Supply of Square-Immune™ - 5 Doses | ✅ | ✅ | 5 Dose | $149.00! (Usually $295.00) |
Square-Immune™ Subscription - 1x every 3 Months | ✅ | ✅ | 1 Dose Every 3 Months on a Subscription | $44.00! (Usually $59.00) |
90-day guarantee! If your symptoms are not better after 90 days, we will refund 100%






Meet the Founder
Dr. Hugh McTavish
Dr. Hugh McTavish is a scientist, innovator, and problem-solver—driven by personal experience to create solutions that work. A Ph.D. biochemist, he founded Square-Immune after developing a treatment for his own frequent cold sores. When it worked for him, he knew it could help others!
Square-Immuneâ„¢ Customers
How to Apply Square-Immuneâ„¢
See how easy it is to apply Square-Immuneâ„¢ and start preventing your outbreaks today!
One dose improves immune response for three months so we recommend applying it once every three months. Some customers find that applying additional doses between their regular three-month applications works even better. If you want to apply additional doses, we recommend the 1-year supply, which is a larger amount of Square-Immuneâ„¢ that allows you to apply doses when you want.